Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147261 | 0.90 | LMNA (0.62) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10394450 | 0.90 | LMNA (0.52) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2580982 | 0.90 | LMNA (0.52) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Nonanol SCHEMBL30396976 | 0.86 | LMNA (0.81) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31257990 | 0.86 | LMNA (0.81) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1329750 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL16209877 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1937969 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10841725 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10841183 | 0.86 | TSHR (0.57) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358795-A1 | SURFACE MODIFICATION OF POLYMERS VIA SURFACE ACTIVE AND REACTIVE END GROUPS | DSM IP Assets B.V. (NL) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010057080-A1 | SURFACE MODIFICATION OF POLYMERS VIA SURFACE ACTIVE AND REACTIVE END GROUPS | DSM IP ASSETS B.V. (NL) | 2010-05-20 | — | — | WO | disclosed |