Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 2/20 | 0.46 |
| ▸ | CD40LG | P29965 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156385 | 1.00 | CD40 (0.46) | CD40CD40LGENPP2KMT2AMEN1 | |
| SCHEMBL11440007 | 0.95 | APEX1 (0.44) | CD40CD40LGENPP2KMT2AMEN1 | |
| SCHEMBL11418896 | 0.95 | APEX1 (0.44) | CD40CD40LGENPP2KMT2AMEN1 | |
| SCHEMBL11152668 | 0.95 | APEX1 (0.44) | CD40CD40LGENPP2KMT2AMEN1 | |
| SCHEMBL11418887 | 0.94 | APEX1 (0.43) | CD40CD40LGENPP2KMT2AMEN1 | |
| SCHEMBL11437296 | 0.88 | MEN1 (0.50) | KMT2AMEN1MAPTPOLBGAA | |
| SCHEMBL11433142 | 0.87 | APEX1 (0.56) | CD40CD40LGENPP2KMT2AMEN1 | |
| SCHEMBL11437291 | 0.86 | MAPT (0.44) | CD40CD40LGKMT2AMEN1MAPT | |
| SCHEMBL11432542 | 0.86 | APEX1 (0.44) | CD40CD40LGKMT2AMEN1TIMP3 | |
| SCHEMBL11442053 | 0.86 | APEX1 (0.44) | CD40CD40LGKMT2AMEN1TIMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387059-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4185032-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |