Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CD40 | P25942 | 2/20 | 0.43 |
| ▸ | CD40LG | P29965 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432542 | 1.00 | APEX1 (0.44) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11514072 | 0.91 | KMT2A (0.46) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11152668 | 0.91 | APEX1 (0.44) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11440007 | 0.91 | APEX1 (0.44) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11418896 | 0.91 | APEX1 (0.44) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11418887 | 0.90 | APEX1 (0.43) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11514077 | 0.88 | RAB9A (0.44) | APEX1CD40CD40LGALDH1A1CYP3A4 | |
| SCHEMBL11437623 | 0.87 | TIMP3 (0.47) | CD40CD40LGALDH1A1CYP3A4NPSR1 | |
| SCHEMBL11147311 | 0.86 | CD40 (0.46) | APEX1CD40CD40LGALDH1A1RAB9A | |
| SCHEMBL11156385 | 0.86 | CD40 (0.46) | APEX1CD40CD40LGALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |