Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
| ▸ | CD40LG | P29965 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437296 | 0.93 | MEN1 (0.50) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11432314 | 0.89 | SMN1; SMN2 (0.51) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11405692 | 0.88 | IDH1 (0.42) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL11147311 | 0.86 | CD40 (0.46) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11156385 | 0.86 | CD40 (0.46) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11415799 | 0.86 | NHERF1 (0.46) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11432038 | 0.86 | CASP6 (0.40) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL11152668 | 0.83 | APEX1 (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11440007 | 0.83 | APEX1 (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11418896 | 0.83 | APEX1 (0.44) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229372-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4155931-A | COMPLEMENT INHIBITORS FOR MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |