Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149361 | 0.92 | MAPT (0.54) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11146339 | 0.91 | PLK1 (0.55) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL53437 | 0.90 | MAPT (0.60) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11146320 | 0.89 | MAPT (0.58) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11193309 | 0.89 | PLK1 (0.60) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11151339 | 0.86 | MAPT (0.55) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11319357 | 0.86 | PLK1 (0.66) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11146334 | 0.85 | MAPT (0.54) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11149337 | 0.84 | MAPT (0.53) | MAPTLMNAPOLBKMT2ARAB9A | |
| SCHEMBL11155449 | 0.83 | MAPT (0.54) | MAPTLMNAPOLBKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385927-A | ETHER OF N-2,3-DICHLOROPHENYL P-HYDROXYBENZAMIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-05-31 | — | — | US | disclosed |