Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149361 | 0.94 | MAPT (0.54) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11193309 | 0.94 | PLK1 (0.60) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11146334 | 0.92 | MAPT (0.54) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11319357 | 0.91 | PLK1 (0.66) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11147514 | 0.91 | MAPT (0.57) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11146320 | 0.87 | MAPT (0.58) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL9621389 | 0.87 | MAPT (0.68) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL11151339 | 0.86 | MAPT (0.55) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL9499050 | 0.86 | MAPT (0.49) | PLK1MAPTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL53437 | 0.83 | MAPT (0.60) | MAPTLMNAPOLBSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385927-A | ETHER OF N-2,3-DICHLOROPHENYL P-HYDROXYBENZAMIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-05-31 | — | — | US | disclosed |