Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.47 |
| ▸ | AMY2A | P04746 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.32 |
| ▸ | SELE | P16581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18755187 | 1.00 | AMY1A (0.47) | AMY1AAMY2AALDH1A1MAPTALOX15 | |
| SCHEMBL11147765 | 1.00 | AMY1A (0.47) | AMY1AAMY2AALDH1A1MAPTALOX15 | |
| SCHEMBL2236730 | 1.00 | AMY1A (0.47) | AMY1AAMY2AALDH1A1MAPTALOX15 | |
| SCHEMBL19335015 | 0.90 | AMY1A (0.50) | AMY1AAMY2AALDH1A1MAPTALOX15 | |
| SCHEMBL8915660 | 0.89 | AMY1A (0.48) | AMY1AAMY2AALDH1A1GAAMGAM | |
| SCHEMBL21884068 | 0.89 | AMY1A (0.48) | AMY1AAMY2AALDH1A1GAAMGAM | |
| SCHEMBL21883716 | 0.89 | AMY1A (0.48) | AMY1AAMY2AALDH1A1GAAMGAM | |
| SCHEMBL2233156 | 0.86 | AMY1A (0.46) | AMY1AAMY2AALDH1A1MAPTALOX15 | |
| SCHEMBL2868914 | 0.86 | AMY1A (0.46) | AMY1AAMY2AALDH1A1MAPTALOX15 | |
| SCHEMBL16904113 | 0.86 | AMY1A (0.48) | AMY1AAMY2AALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4388457-A | ANTINEOPLASTIC GLYCOSIDES | UNIVERSITY PATENTS, INC. (US) | 1983-06-14 | — | — | US | disclosed |