Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | AMY2A | P04746 | 4/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868914 | 1.00 | AMY1A (0.46) | AMY1AAMY2AFASNPTGS1PTGS2 | |
| SCHEMBL17862037 | 0.90 | AMY1A (0.46) | AMY1AFASNPTGS1PTGS2ALDH1A1 | |
| SCHEMBL17862025 | 0.88 | AMY1A (0.44) | AMY1AFASNPTGS1PTGS2ALDH1A1 | |
| SCHEMBL19335015 | 0.88 | AMY1A (0.50) | AMY1AAMY2AFASNPTGS1PTGS2 | |
| SCHEMBL8915660 | 0.87 | AMY1A (0.48) | AMY1AAMY2APTGS1ALDH1A1GAA | |
| SCHEMBL21884068 | 0.87 | AMY1A (0.48) | AMY1AAMY2APTGS1ALDH1A1GAA | |
| SCHEMBL21883716 | 0.87 | AMY1A (0.48) | AMY1AAMY2APTGS1ALDH1A1GAA | |
| SCHEMBL11147760 | 0.86 | AMY1A (0.47) | AMY1AAMY2AFASNPTGS1PTGS2 | |
| SCHEMBL18755187 | 0.86 | AMY1A (0.47) | AMY1AAMY2AFASNPTGS1PTGS2 | |
| SCHEMBL11147765 | 0.86 | AMY1A (0.47) | AMY1AAMY2AFASNPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013024905-A1 | COMBINATION DRUG OF ANTIBODY AGAINST LIPOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA AND ANTIBACTERIAL AGENT | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2013-02-21 | — | — | WO | disclosed |
| WO-2011102552-A1 | ANTIBODY AGAINST A BAND LIPOPOLYSACCHARIDE OF PSEUDOMONAS AERUGINOSA | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-08-25 | — | — | WO | disclosed |