Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80318 | 0.88 | GABRA1 (0.59) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL10592782 | 0.83 | GABRA1 (0.46) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL28258628 | 0.82 | GABRA1 (0.44) | GABRA1GABRB2 | |
| SCHEMBL28260919 | 0.80 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL693019 | 0.78 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL583713 | 0.77 | CYP3A4 (0.65) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL5916108 | 0.75 | GABRA1 (0.45) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL28258622 | 0.75 | GABRA1 (0.39) | GABRA1GABRB2 | |
| SCHEMBL14946937 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL11415298 | 0.73 | GABRA1 (0.53) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4423200-A | FROM POLYURETHANE AND CHAIN EXTENDING AROMATIC DIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |