SCHEMBL11148024

SCHEMBL11148024

O=P(CCCS)(OC1CCCCC1)OC1CCCCC1

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.40
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6361086 0.83 ACHE (0.48) ACHENPSR1MEN1KMT2ALMNA
SCHEMBL4449156 0.81 ACHE (0.40) ACHENPSR1MEN1KMT2ALMNA
SCHEMBL28982523 0.81 ACHE (0.40) ACHENPSR1MEN1KMT2ALMNA
SCHEMBL4451300 0.81 ACHE (0.44) ACHENPSR1MEN1KMT2A
SCHEMBL28674349 0.79 ACHE (0.39) ACHENPSR1MEN1KMT2ALMNA
SCHEMBL4455006 0.79 ACHE (0.39) ACHENPSR1MEN1KMT2ALMNA
SCHEMBL4455004 0.78 ACHE (0.38) ACHE
SCHEMBL9249996 0.77 NAAA (0.43) ACHE
SCHEMBL28982521 0.76 ACHE (0.42) ACHENPSR1MEN1KMT2ALMNA
SCHEMBL4460516 0.76 ACHE (0.42) ACHENPSR1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4401535-A REACTING A DIALKYL ALKENYL PHOSPHONATE WITH HYDROGEN SULFIDE USING ACTINIC LIGHT; VULCANIZATION PHILLIPS PETROLEUM COMPANY (US) 1983-08-30 US disclosed
US-4386185-A DIHYDROCARBYL MERCJAPTOALKYLPHOSPHONATE PHILLIPS PETROLEUM COMPANY (US) 1983-05-31 US disclosed
US-4359342-A Silica reinforced rubber PHILLIPS PETROLEUM COMPANY (US) 1982-11-16 US disclosed