Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADIPOR2 | Q86V24 | 1/20 | 0.47 |
| ▸ | ADIPOR1 | Q96A54 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11255924 | 0.99 | ADIPOR2 (0.46) | ADIPOR2ADIPOR1ALDH1A1CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL11144955 | 0.98 | ADIPOR2 (0.45) | ADIPOR2ADIPOR1ALDH1A1CARM1PRMT6 | |
| SCHEMBL11142321 | 0.91 | CARM1 (0.58) | CARM1PRMT6SCN1ASCN5ASCN9A | |
| SCHEMBL11142334 | 0.90 | ALDH1A1 (0.55) | ALDH1A1LTA4H | |
| Hydrochloric Acid SCHEMBL11144305 | 0.89 | PTGS1 (0.44) | ALDH1A1CARM1PRMT6SCN1ASCN5A | |
| SCHEMBL11143476 | 0.89 | ALDH1A1 (0.47) | ADIPOR2ADIPOR1ALDH1A1CARM1PRMT6 | |
| SCHEMBL11141846 | 0.89 | ADIPOR2 (0.50) | ADIPOR2ADIPOR1ALDH1A1CARM1PRMT6 | |
| SCHEMBL11142787 | 0.87 | ALDH1A1 (0.50) | ALDH1A1LTA4H | |
| SCHEMBL11144343 | 0.87 | ADIPOR2 (0.48) | ADIPOR2ADIPOR1ALDH1A1CARM1PRMT6 | |
| SCHEMBL11137457 | 0.87 | ALDH1A1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4396765-A | ANTIASTHMATICS, BRONCHODILATORS | STERLING DRUG INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4339576-A | Anti-asthmatic, anti-allergic, anti-cholinergic, bronchodilator and anti-inflammatory 1-[(benzoylphenyl)-lower-alkyl]piperidines and analogs thereof | STERLING DRUG INC. (US) | 1982-07-13 | — | — | US | disclosed |
| EP-0052311-A1 | 1-((Benzoylphenyl) - lower-alkyl) piperidines and carbinol analogs and preparation thereof | STERLING DRUG INC. (US) | 1982-05-26 | — | — | EP | disclosed |
| US-4304911-A | ANTIHISTAMINES, ANTIALLERGENS, ANTICHOLINERGIC AGENTS, ANTIINFLAMMATORY AGENTS, BRONCHODILATOR AGENTS, AND ANALGESICS | STERLING DRUG INC. (US) | 1981-12-08 | — | — | US | disclosed |