SCHEMBL11148596

SCHEMBL11148596

O=C(O)C1C=Cc2c(O)cccc2C1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.37
ALOX15 P16050 4/20 0.37
ALDH1A1 P00352 4/20 0.37
HPGD P15428 4/20 0.37
HSD17B10 Q99714 4/20 0.37
KDM4E B2RXH2 4/20 0.37
RECQL P46063 4/20 0.37
KMT2A Q03164 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
MEN1 O00255 3/20 0.37
THRB P10828 3/20 0.37
MAPK1 P28482 2/20 0.37
CYP3A4 P08684 2/20 0.37
CASP1 P29466 2/20 0.37
BLM P54132 2/20 0.37
CASP7 P55210 2/20 0.37
USP2 O75604 2/20 0.37
AURKA O14965 1/20 0.37
TRPA1 O75762 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2405597 0.82 EDNRB (0.33) MAPTALOX15MAPK1CYP3A4TP53
SCHEMBL16554367 0.74 EDNRB (0.41) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL30436927 0.66 MAPT (0.63) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL27677826 0.66 MAPT (0.63) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL30496126 0.63 MAPT (0.53) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL10409093 0.63 MAPT (0.53) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL10601750 0.63 EDNRA (0.44) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL2404764 0.62 PTPRC (0.33) MMP2
SCHEMBL2406293 0.62 CA12 (0.36) MAPTALOX15ALDH1A1HPGDHSD17B10
SCHEMBL2403993 0.62 ALDH1A1 (0.33) MAPTALOX15ALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4370397-A Presensitized plastic card, tamperproof identification card prepared therefrom, and process for manufacture of tamperproof identification card RHONE-POULENC SYSTEMES (FR) 1983-01-25 US disclosed
US-3950171-A THERMOPLASTIC RESIN DIAZONIUM SALT MITA INDUSTRIAL CO. LTD. (JA) 1976-04-13 US disclosed
US-3948661-A Process for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LTD. (JA) 1976-04-06 US disclosed
US-3944422-A Photosensitive material in use for diazo-type multicolor reproduction MITA INDUSTRIAL COMPANY LIMITED (JA) 1976-03-16 US disclosed