SCHEMBL2403993

SCHEMBL2403993

Nc1ccc2c(c1)C(=O)C(C(=O)O)C=C2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
CYP3A4 P08684 3/20 0.33
TDP1 Q9NUW8 3/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
GAA P10253 2/20 0.33
CASP1 P29466 2/20 0.33
HSD17B10 Q99714 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 4/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
POLB P06746 2/20 0.33
THRB P10828 2/20 0.33
RECQL P46063 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2406293 0.87 CA12 (0.36) ALDH1A1MEN1KMT2ACYP3A4TDP1
SCHEMBL16554367 0.76 EDNRB (0.41) ALDH1A1MEN1KMT2ACYP3A4NPC1
SCHEMBL2202782 0.71 TTR (0.41) ALDH1A1MEN1KMT2ATDP1GAA
SCHEMBL2404764 0.68 PTPRC (0.33) PTPRC
SCHEMBL4530422 0.67 MEN1 (0.33) ALDH1A1MEN1KMT2ACYP3A4TDP1
SCHEMBL11927527 0.65 PTPRC (0.44) ALDH1A1MEN1KMT2ACYP3A4TDP1
SCHEMBL8147531 0.62 PTPRC (0.60) ALDH1A1MEN1KMT2ACYP3A4TDP1
SCHEMBL2405018 0.62 MAPT (0.33) ALDH1A1MEN1KMT2ACYP3A4TDP1
SCHEMBL11148596 0.62 MAPT (0.37) ALDH1A1MEN1KMT2ACYP3A4TDP1
SCHEMBL6215765 0.62 MAPT (0.39) ALDH1A1MEN1KMT2ACYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592071-B2 Laminated porous film and separator for battery MITSUBISHI PLASTICS, INC. (JP) 2013-11-26 US disclosed
US-20110212358-A1 LAMINATED POROUS FILM AND SEPARATOR FOR BATTERY MITSUBISHI PLASTICS, INC. (JP) 2011-09-01 US disclosed