Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.65 |
| ▸ | DRD3 | P35462 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11154433 | 0.99 | DRD2 (0.64) | DRD2DRD3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL11146184 | 0.92 | DRD2 (0.65) | DRD2DRD3HRH1SLC6A2HRH2 | |
| SCHEMBL11147626 | 0.87 | DRD2 (0.60) | DRD2DRD3HRH1SLC6A2HTR2A | |
| SCHEMBL11148465 | 0.87 | DRD2 (0.71) | DRD2DRD3ALDH1A1ALDH2ALDH3A1 | |
| Hydrochloric Acid SCHEMBL11152426 | 0.86 | DRD2 (0.58) | DRD2DRD3ALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11155916 | 0.86 | DRD2 (0.58) | DRD2DRD3ALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL11147710 | 0.85 | DRD2 (0.70) | DRD2DRD3ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL11147296 | 0.85 | DRD2 (0.63) | DRD2DRD3ALDH1A1TDP1 | |
| SCHEMBL11154465 | 0.85 | DRD2 (0.63) | DRD2DRD3DRD4 | |
| SCHEMBL11151708 | 0.85 | DRD2 (0.63) | DRD2DRD3ALDH1A1ALDH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | claimed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | claimed |
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |