Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | DRD3 | P35462 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11152426 | 0.97 | DRD2 (0.58) | DRD2DRD3ALDH1A1MAPTKMT2A | |
| SCHEMBL11151708 | 0.87 | DRD2 (0.63) | DRD2DRD3ALDH1A1P2RX7POLB | |
| SCHEMBL11154465 | 0.87 | DRD2 (0.63) | DRD2DRD3P2RX7ADRA1B | |
| SCHEMBL11149873 | 0.87 | DRD2 (0.75) | DRD2DRD3ALDH1A1ADRA1BMAOB | |
| SCHEMBL11147571 | 0.85 | DRD2 (0.73) | DRD2DRD3ALDH1A1P2RX7ADRA1B | |
| SCHEMBL11147626 | 0.85 | DRD2 (0.60) | DRD2DRD3KMT2AP2RX7LMNA | |
| SCHEMBL11149249 | 0.85 | DRD2 (0.65) | DRD2DRD3ALDH1A1TDP1 | |
| SCHEMBL11144976 | 0.85 | PARK7 (0.57) | DRD2DRD3ALDH1A1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL11153700 | 0.84 | DRD2 (0.72) | DRD2DRD3ALDH1A1POLBADRA1B | |
| SCHEMBL11148465 | 0.84 | DRD2 (0.71) | DRD2DRD3ALDH1A1POLBADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |