Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16027109 | 0.83 | LMNA (0.63) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL1114668 | 0.82 | LMNA (0.67) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL16063779 | 0.81 | LMNA (0.63) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| Hydrochloric Acid SCHEMBL1114457 | 0.81 | LMNA (0.74) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL1114391 | 0.80 | LMNA (0.62) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL1114669 | 0.80 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL1114497 | 0.80 | DRD2 (0.72) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL12403673 | 0.80 | LMNA (0.72) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL1114603 | 0.79 | LMNA (0.63) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 | |
| SCHEMBL1114565 | 0.79 | LMNA (0.63) | LMNAALDH1A1SMN1; SMN2MAPTNLRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279179-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK Holdings Co., Ltd. (KR) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009145591-A2 | PHENYL PIPERAZINE COMPOUNDS, PHARMACEUTICAL COMPOSITION INCLUDING THE SAME, AND USE THEREOF | SK HOLDINGS CO., LTD. (KR) | 2009-12-03 | — | — | WO | disclosed |