Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | DRD3 | P35462 | 7/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11150520 | 0.82 | DRD2 (0.58) | DRD2DRD3P2RX7MEN1MLNR | |
| Hydrochloric Acid SCHEMBL11151692 | 0.81 | DRD2 (0.63) | DRD2DRD3P2RX7MEN1MLNR | |
| Hydrochloric Acid SCHEMBL11149507 | 0.81 | DRD2 (0.63) | DRD2DRD3P2RX7MEN1LMNA | |
| SCHEMBL11148465 | 0.80 | DRD2 (0.71) | DRD2DRD3PKMADRA1BMAOB | |
| Hydrochloric Acid SCHEMBL11149834 | 0.79 | DRD3 (0.60) | DRD2DRD3P2RX7MEN1MLNR | |
| Hydrochloric Acid SCHEMBL11149417 | 0.79 | DRD2 (0.57) | DRD2DRD3P2RX7MEN1MLNR | |
| Hydrochloric Acid SCHEMBL11147710 | 0.79 | DRD2 (0.70) | DRD2DRD3P2RX7MEN1MLNR | |
| SCHEMBL11146184 | 0.79 | DRD2 (0.65) | DRD2DRD3P2RX7MEN1MLNR | |
| Hydrochloric Acid SCHEMBL11148481 | 0.78 | DRD2 (0.58) | DRD2DRD3P2RX7MEN1MLNR | |
| SCHEMBL7976323 | 0.78 | DRD2 (0.95) | DRD2DRD3MAOBALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382934-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0010398-B1 | ISATIN DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-27 | — | — | EP | disclosed |
| EP-0010398-A1 | Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |