Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.95 |
| ▸ | DRD3 | P35462 | 4/20 | 0.95 |
| ▸ | MAOB | P27338 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10826808 | 0.99 | DRD2 (0.92) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL9256633 | 0.97 | DRD2 (1.00) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL10763449 | 0.95 | DRD2 (0.95) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL9733689 | 0.92 | DRD2 (0.84) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL31232750 | 0.92 | DRD2 (0.84) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL9258386 | 0.90 | DRD2 (0.77) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL6166099 | 0.88 | DRD3 (0.79) | DRD2DRD3MAOBALDH1A1POLB | |
| SCHEMBL9256276 | 0.87 | DRD2 (0.81) | DRD2DRD3MAOBHTR1A | |
| SCHEMBL9256958 | 0.86 | DRD2 (0.79) | DRD2DRD3MAOBHTR1A | |
| SCHEMBL11148465 | 0.86 | DRD2 (0.71) | DRD2DRD3MAOBALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-4673684-A | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO CORPORATION (JP) | 1987-06-16 | — | — | US | disclosed |
| EP-0157420-A2 | Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) | 1985-10-09 | — | — | EP | disclosed |