SCHEMBL111496

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL160426	0.97	CXCR3 (0.51)	CXCR3KCNH2CYP1A2CYP3A4CYP2D6
	SCHEMBL113666	0.90	CXCR3 (0.45)	CXCR3KCNH2LMNATSHRHSD17B10
	SCHEMBL111489	0.90	CXCR3 (0.45)	CXCR3KCNH2LMNA
	SCHEMBL113733	0.90	POLB (0.48)	CXCR3KCNH2CYP2C9CYP2C19LMNA
	SCHEMBL110411	0.90	CXCR3 (0.50)	CXCR3KCNH2CYP1A2CYP3A4CYP2D6
	SCHEMBL159697	0.90	CXCR3 (0.49)	CXCR3KCNH2LMNATSHRKMT2A
	SCHEMBL111887	0.89	CXCR3 (0.45)	CXCR3KCNH2LMNATSHRKMT2A
	SCHEMBL111947	0.86	CCR1 (0.43)	CXCR3KCNH2LMNATSHRKMT2A
	SCHEMBL111638	0.85	CYP1A2 (0.65)	CXCR3KCNH2CYP1A2CYP3A4CYP2D6
	SCHEMBL163721	0.85	CXCR3 (0.51)	CXCR3CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.