SCHEMBL113733

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL111496	0.90	CXCR3 (0.54)	LMNACXCR3KCNH2ALDH1A1MEN1
	SCHEMBL13076822	0.89	CCR1 (0.49)	LMNACXCR3IRAK4CHRM4CHRM5
	SCHEMBL113666	0.88	CXCR3 (0.45)	LMNACXCR3IRAK4KCNH2ALDH1A1
	SCHEMBL160426	0.88	CXCR3 (0.51)	LMNACXCR3KCNH2CYP2C9CYP2C19
	SCHEMBL111489	0.86	CXCR3 (0.45)	LMNACXCR3KCNH2
	SCHEMBL159697	0.86	CXCR3 (0.49)	POLBLMNACXCR3MAPTKCNH2
	SCHEMBL111887	0.85	CXCR3 (0.45)	LMNACXCR3KCNH2ALDH1A1MEN1
	SCHEMBL112176	0.84	TSHR (0.58)	POLBLMNARECQLCXCR3IRAK4
	SCHEMBL111947	0.83	CCR1 (0.43)	LMNACXCR3MAPTKCNH2ALDH1A1
	SCHEMBL110411	0.83	CXCR3 (0.50)	LMNACXCR3KCNH2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.