Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146910 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27055250 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL27055255 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11364943 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11365053 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10966146 | 1.00 | LMNA (0.65) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11125950 | 0.95 | LMNA (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL8135195 | 0.95 | LMNA (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL11147938 | 0.95 | LMNA (0.57) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7517899 | 0.92 | SMN1; SMN2 (0.55) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4416876-A | PHARMACEUTICAL AGENTS | SANDOZ, INC. (US) | 1983-11-22 | — | — | US | disclosed |