Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135195 | 0.97 | LMNA (0.57) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL11146910 | 0.92 | LMNA (0.65) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL11149697 | 0.92 | LMNA (0.65) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL11365053 | 0.92 | LMNA (0.65) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL10966146 | 0.92 | LMNA (0.65) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL11364943 | 0.92 | LMNA (0.65) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL3318616 | 0.92 | ALDH1A1 (0.53) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL11147938 | 0.87 | LMNA (0.57) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL11125950 | 0.87 | LMNA (0.57) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL9034708 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2LMNATSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946477-B1 | DERIVATIVES OF 9,9-DIFLUORO-9,10-DIHYDROPHENANTHRENE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECHNOLOGY GMBH (DE) | 2002-07-31 | — | — | EP | disclosed |
| EP-0946513-B1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-01-30 | — | — | EP | disclosed |
| US-6120703-A | Derivatives of 6-fluorophenanthridine for liquid crystal mixtures | AVENTIS RESEARCH & TECHNOLOGIES DEUTSCHLAND GMBH & CO. KG (DE) | 2000-09-19 | — | — | US | disclosed |
| EP-0946477-A1 | DERIVATIVES OF 9,9-DIFLUORO-9,10-DIHYDROPHENANTHRENE FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG. (DE) | 1999-10-06 | — | — | EP | disclosed |
| EP-0946513-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027043-A1 | DERIVATIVES OF 9,9-DIFLUORO-9,10-DIHYDROPHENANTHRENE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1998-06-25 | — | — | WO | disclosed |
| WO-1998027060-A1 | DERIVATIVES OF 6-FLUOROPHENANTHRIDINE FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-25 | — | — | WO | disclosed |
| EP-0532916-B1 | 2-Fluoropyrazines, process for their preparation, and their use in liquid crystalline mixtures | HOECHST AG (DE) | 1997-11-05 | — | — | EP | disclosed |
| US-5562859-A | SWITCHING AND DISPLAY DEVICE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-08 | — | — | US | disclosed |
| EP-0532916-A1 | 2-Fluoropyrazines, process for their preparation, and their use in liquid crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |