Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | RECQL | P46063 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152310 | 0.88 | KDM4E (0.67) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL10883607 | 0.81 | KDM4E (0.65) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL2069790 | 0.77 | SMN1; SMN2 (0.61) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL10995103 | 0.76 | KDM4E (0.62) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL7498444 | 0.75 | MAPT (0.65) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL2072031 | 0.75 | MAPT (0.65) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL10650560 | 0.73 | KDM4E (0.48) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL11052857 | 0.73 | ADORA3 (0.62) | MAPTKDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL11618736 | 0.73 | MAPT (0.53) | MAPTKDM4ERECQLTDP1LMNA | |
| SCHEMBL1773882 | 0.73 | MAPK1 (0.50) | MAPTKDM4ERECQLTDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |