Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28976989 | 0.72 | IMPDH2 (0.48) | IMPDH2GAAAXLEP300KAT2B | |
| SCHEMBL197023 | 0.70 | GAA (0.52) | IMPDH2GAAAXLEP300KAT2B | |
| SCHEMBL31468033 | 0.68 | IMPDH2 (0.41) | IMPDH2GAAAXLEP300KAT2B | |
| SCHEMBL793650 | 0.68 | IMPDH2 (0.41) | IMPDH2GAAAXLEP300KAT2B | |
| SCHEMBL8904180 | 0.68 | CYP2A6 (0.47) | CYP2A6KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL15676238 | 0.67 | KIT (0.50) | GAAAXLEP300KAT2BKAT8 | |
| SCHEMBL11884982 | 0.67 | CYP2A6 (0.42) | AXLEP300KAT2BKAT8CYP2A6 | |
| SCHEMBL11885002 | 0.67 | KDM4E (0.44) | IMPDH2GAAAXLEP300KAT2B | |
| SCHEMBL1652259 | 0.67 | AXL (0.45) | IMPDH2GAAAXLEP300KAT2B | |
| SCHEMBL10809410 | 0.67 | IMPDH2 (0.39) | IMPDH2GAAAXLEP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043573-B1 | PROCESS FOR THE PREPARATION OF 2,6-DICHLOROBENZOXAZOLE OR 2,6-DICHLOROBENZTHIAZOLE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-31 | — | — | EP | claimed |
| EP-0043573-B1 | PROCESS FOR THE PREPARATION OF 2,6-DICHLOROBENZOXAZOLE OR 2,6-DICHLOROBENZTHIAZOLE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-31 | — | — | EP | disclosed |
| EP-0043573-A1 | Process for the preparation of 2,6-dichlorobenzoxazole or 2,6-dichlorobenzthiazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-13 | — | — | EP | disclosed |