SCHEMBL28976989

SCHEMBL28976989

Clc1c2ccncc2c(Cl)c2ccncc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.48
GAA P10253 1/20 0.42
AXL P30530 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT8 Q9H7Z6 1/20 0.40
CHUK O15111 5/20 0.39
NFATC1 O95644 1/20 0.38
GSK3B P49841 1/20 0.38
DYRK1A Q13627 1/20 0.38
CDC25B P30305 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ACHE P22303 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
MAPKAPK2 P49137 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20869623 0.85 EP300 (0.44) IMPDH2GAAAXLEP300KAT2B
Bromide SCHEMBL20854640 0.84 EP300 (0.42) IMPDH2GAAAXLEP300KAT2B
SCHEMBL197023 0.76 GAA (0.52) IMPDH2GAAAXLEP300KAT2B
SCHEMBL21297743 0.74 KIT (0.47) GAAAXLEP300KAT2BKAT8
SCHEMBL31468033 0.74 IMPDH2 (0.41) IMPDH2GAAAXLEP300KAT2B
SCHEMBL793650 0.74 IMPDH2 (0.41) IMPDH2GAAAXLEP300KAT2B
SCHEMBL15676238 0.72 KIT (0.50) GAAAXLEP300KAT2BKAT8
SCHEMBL11150652 0.72 IMPDH2 (0.39) IMPDH2GAAAXLEP300KAT2B
SCHEMBL10809410 0.72 IMPDH2 (0.39) IMPDH2GAAAXLEP300KAT2B
SCHEMBL21297750 0.70 KDM4E (0.49) GAAAXLEP300KAT2BKAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082369-A Organic electroluminescent material based on triazolopyridine and organic electroluminescent device 武汉尚赛光电科技有限公司 2023-05-09 CN disclosed
CN-110452689-B Triazolopyridine-based organic electroluminescent material and organic electroluminescent device 武汉尚赛光电科技有限公司 2023-02-28 CN disclosed