SCHEMBL1115089

SCHEMBL1115089

O=C(c1c2ccccc2cc2ccccc12)C(CC(=O)C(F)(F)F)C(=O)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
HPGD P15428 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GLA P06280 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.40
CPA1 P15085 1/20 0.39
CES1 P23141 1/20 0.36
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
ME2 P23368 1/20 0.34
ME1 P48163 1/20 0.34
ME3 Q16798 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6568049 0.83 KDM4E (0.48) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL2697287 0.74 MEN1 (0.50) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL6081630 0.71 ALDH1A1 (0.59) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL21939675 0.68 ALDH1A1 (0.59) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL2697711 0.64 KMT2A (0.53) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL2697713 0.64 KMT2A (0.53) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL13120116 0.63 ALDH1A1 (0.52) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL14497162 0.63 PLOD2 (0.42) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL4899613 0.63 ALDH1A1 (0.68) KDM4EALDH1A1HPGDMEN1KMT2A
Anthracene-9-Carboxylic Acid SCHEMBL29352186 0.63 MEN1 (1.00) KDM4EALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1848786-B1 ELECTROLUMINESCENT MATERIALS AND DEVICES MERCK PATENT GMBH (DE) 2011-02-02 EP disclosed
US-7811676-B2 Electroluminescent materials and devices MERCK PATENT GMBH (DE) 2010-10-12 US disclosed
US-7767315-B2 Incorporating a fluorescent organometallic complex in the toner or in the paper in which the fluorescent dye gives off light with a characteristic spectrum when exposed to ultraviolet light; authenticated at room temperature; strong emission which can be digitized; paper, cloth, and plastic MERCK PATENT GMBH (DE) 2010-08-03 US disclosed
US-20100038632-A1 ELECTROLUMINESCENT DEVICE OLED-T LIMITED (GB) 2010-02-18 US disclosed
US-20090167158-A1 Electroluminescent Devices MERCK PATENT GMBH (DE) 2009-07-02 US disclosed
EP-2044170-A1 ELECTROLUMINESCENT DEVICE Merck Patent GmbH (DE) 2009-04-08 EP disclosed
US-20090009062-A1 Electroluminescent Devices MERCK PATENT GMBH (DE) 2009-01-08 US disclosed
US-20080265210-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2008-10-30 US disclosed
US-20080199727-A1 Electroluminescent devices with an improved buffer layer on the anode; buffer selected from metal tetra-p-tolyl porphonato complexes and bianthryl compounds; reduction or elimination of mobile counterions in an organic electronic device; avoidance of undesirable operating voltage increase over time OLED-T LIMITED (GB) 2008-08-21 US disclosed
EP-1946392-A2 ELECTROLUMINESCENT DEVICES OLED-T LIMITED (GB) 2008-07-23 EP disclosed
WO-2003067679-A1 METHOD FOR FORMING ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2003-08-14 WO disclosed
WO-2003038010-A1 DOCUMENT AUTHENTIFICATION ELAM-T LIMITED (GB) 2003-05-08 WO disclosed
WO-2003014256-A1 ELECTROLUMINESCENT DEVICE ELAM-T LIMITED (GB) 2003-02-20 WO disclosed
WO-2002102924-A2 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-12-27 WO disclosed
WO-2002091493-A2 ELECTROLUMINESCENT DEVICE ELAM-T LIMITED (GB) 2002-11-14 WO disclosed
WO-2002090466-A1 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-11-14 WO disclosed
WO-2002086015-A2 MIXED METAL ORGANIC COMPLEXES ELAM-T LIMITED (GB) 2002-10-31 WO disclosed
WO-2002087283-A1 ELECTROLUMINESCENT DEVICES INCORPORATING MIXED METAL ORGANIC COMPLEXES ELAM-T LIMITED (GB) 2002-10-31 WO disclosed
WO-2002075820-A1 ELECTROLUMINESCENT DEVICES ELAM-T LIMITED (GB) 2002-09-26 WO disclosed
WO-2002043446-A1 ELECTROLUMINESCENT DEVICE ELAM-T LIMIED (GB) 2002-05-30 WO disclosed