Pentamustine

Pentamustine

SCHEMBL11151237

CC(C)(C)CNC(=O)N(CCCl)N=O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
BLM P54132 2/20 0.64
PMP22 Q01453 2/20 0.64
MEN1 O00255 1/20 0.64
ABCB11 O95342 1/20 0.64
GSR P00390 1/20 0.64
TSHR P16473 1/20 0.64
HTT P42858 1/20 0.64
KMT2A Q03164 1/20 0.64
ADRA2A P08913 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PDE4A P27815 1/20 0.47
ADRA1A P35348 1/20 0.47
LMNA P02545 1/20 0.44
NFKB1 P19838 1/20 0.44
EGFR P00533 1/20 0.31
ERBB2 P04626 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4261 0.86 ALDH1A1 (0.44) ALDH1A1BLMPMP22MEN1ABCB11
SCHEMBL11148427 0.85 ALDH1A1 (0.72) ALDH1A1BLMPMP22MEN1ABCB11
SCHEMBL11148768 0.83 ALDH1A1 (0.42) ALDH1A1BLMPMP22MEN1ABCB11
SCHEMBL25763748 0.79 ALDH1A1 (0.58) ALDH1A1BLMPMP22MEN1ABCB11
Carmustine SCHEMBL4503 0.78 ALDH1A1 (1.00) ALDH1A1BLMPMP22MEN1ABCB11
Carmustine SCHEMBL2047318 0.78 ALDH1A1 (1.00) ALDH1A1BLMPMP22MEN1ABCB11
SCHEMBL9013052 0.78 ALDH1A1 (0.57) ALDH1A1BLMPMP22MEN1ABCB11
SCHEMBL10005923 0.77 ALDH1A1 (0.77) ALDH1A1BLMPMP22MEN1ABCB11
Elmustine SCHEMBL93476 0.77 ALDH1A1 (0.82) ALDH1A1BLMPMP22MEN1ABCB11
SCHEMBL26638056 0.76 ALDH1A1 (0.63) ALDH1A1BLMPMP22MEN1ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3441089-B1 TREATMENT METHODS USING ADENOVIRUS VASCULAR BIOGENICS LTD (IL) 2022-12-14 EP claimed
CN-111202849-B Albumin-bound nitrosourea antitumor pharmaceutical preparation and preparation method thereof 四川大学 2022-06-03 CN claimed
CN-1733301-A Anticancer implantation agent KONG QINGZHONG (CN) 2006-02-15 CN claimed
CN-1679950-A Anticarcinogenic internal implant agent LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
WO-2025096952-A1 SCAFFOLDS AND SCAFFOLD HOLDERS FOR TISSUE ENGINEERING UNIVERSITY OF CONNECTICUT (US) 2025-05-08 WO disclosed
WO-2025059533-A1 CRISPR ENZYMES AND SYSTEMS THE BROAD INSTITUTE, INC. (US) 2025-03-20 WO disclosed
WO-2025043125-A1 METHODS AND DEVICES FOR CANDIDATE DERIVATION FOR AFFINE MERGE MODE IN VIDEO CODING Beijing Dajia Internet Information Technology Co., Ltd. (CN) 2025-02-27 WO disclosed
CN-119418421-A Outdoor activity management system based on cloud service 西藏爱乐福文化发展有限公司 2025-02-11 CN disclosed
CN-119087347-A Direct positioning method with site error and external correction source 中国电子科技集团公司第三十六研究所 2024-12-06 CN disclosed
CN-119087348-A Direct positioning method for radiation source position 中国电子科技集团公司第三十六研究所 2024-12-06 CN disclosed
CN-119087346-A Direct positioning method under condition of station address error 中国电子科技集团公司第三十六研究所 2024-12-06 CN disclosed
WO-2024049520-A1 SYSTEM AND METHOD OF EXTRUDING A HEMP COMPOSITE BOARD USING HEMP FEEDSTOCKS GRAHAM JOHN D (US) 2024-03-07 WO disclosed
CN-101327186-A Anticancer implantation agent JINAN SHUAIHUA PHARMACEUTICAL (CN) 2008-12-24 CN disclosed
CN-101249066-A Sustained-release agent containing hormone anti-cancer medicine JINAN KANGQUAN PHARMACEUTICAL (CN) 2008-08-27 CN disclosed
CN-100340297-C Anticarcinogenic internal implant agent LANJIN BIOLOG ENGINEERING CO L (CN) 2007-10-03 CN disclosed
CN-1846670-A Anticancer implant JINAN SHUAIHUA MEDICINE SCI TE (CN) 2006-10-18 CN disclosed
CN-1824314-A Slow-release agent containing hormone anticancer medicine JINAN KANGQUAN MEDICINE SCI & (CN) 2006-08-30 CN disclosed
CN-1733301-A Anticancer implantation agent KONG QINGZHONG (CN) 2006-02-15 CN disclosed
CN-1679950-A Anticarcinogenic internal implant agent LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN disclosed
US-4423076-A ANTICARCINOGENIC AGENTS NATIONAL FOUNDATION FOR CANCER RESEARCH, INC. (US) 1983-12-27 US disclosed