Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | CNR1 | P21554 | 8/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145789 | 0.83 | ALDH1A1 (0.57) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11149057 | 0.76 | ALDH1A1 (0.59) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11151040 | 0.74 | ALDH1A1 (0.56) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11149089 | 0.71 | ALDH1A1 (0.71) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11154817 | 0.70 | MAPK8 (0.47) | KDM4EALDH1A1CNR2CNR1LMNA | |
| SCHEMBL11144945 | 0.70 | ALDH1A1 (0.60) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5777179 | 0.70 | ALDH1A1 (0.48) | KDM4EKMT2AALDH1A1HPGDLMNA | |
| SCHEMBL11152267 | 0.69 | LMNA (0.41) | KDM4EMEN1KMT2AALDH1A1CNR2 | |
| SCHEMBL11149155 | 0.68 | POLB (0.42) | KDM4EALDH1A1HPGDCNR2LMNA | |
| SCHEMBL11154823 | 0.68 | POLB (0.46) | KDM4EALDH1A1HPGDLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |