SCHEMBL11152467

SCHEMBL11152467

CCCCC(C)S(=O)(=O)OOC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
ALDH1A1 P00352 1/20 0.35
SLC15A1 P46059 1/20 0.35
CA2 P00918 4/20 0.34
CA1 P00915 4/20 0.34
MAPK1 P28482 1/20 0.33
DPP7 Q9UHL4 3/20 0.33
DPP8 Q6V1X1 2/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
RECQL P46063 1/20 0.32
FAAH O00519 2/20 0.32
PLA2G2C Q5R387 1/20 0.31
DPP4 P27487 1/20 0.31
DPP9 Q86TI2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8896863 0.95 TP53 (0.46) TP53ALDH1A1CA1FAAH
SCHEMBL11584275 0.93 TP53 (0.44) TP53CA1FAAH
SCHEMBL11149841 0.81 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11585502 0.80
SCHEMBL11509034 0.77 TP53 (0.52) TP53CA2CA1
SCHEMBL28498613 0.75 TP53 (0.47) TP53CA1FAAH
SCHEMBL11586435 0.74 CA2 (0.33) ALDH1A1CA2CA1MAPK1RECQL
SCHEMBL6113083 0.74 TP53 (0.43) TP53SLC15A1CA2CA1MAPK1
SCHEMBL11425554 0.72 TSHR (0.36) ALDH1A1
SCHEMBL11586339 0.71 ZDHHC7 (0.47) ALDH1A1CA2CA1FAAHPLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4374057-A IN SUSPENDING AGENT, WETTING AGENT AND ANTIFREEZE; STORAGE STABILITY TENNECO CHEMICALS, INC. (US) 1983-02-15 US disclosed
US-4101464-A Process for preparing foamed solids using two or more azo compounds PENNWALT CORPORATION (US) 1978-07-18 US disclosed
US-4069377-A Polymerization of ethylenically unsaturated monomers employing secondary-aliphatic α-substituted azoalkanes PENNWALT CORPORATION 1978-01-17 US disclosed
US-4029615-A AZO COMPOUNDS PENNWALT CORPORATION (US) 1977-06-14 US disclosed
US-4028344-A FOAMING AGENTS, FREE RADICAL INITIATORS PENNWALT CORPORATION (US) 1977-06-07 US disclosed
US-4025502-A POLYMERIZATION CATALYSTS, CURING AGENTS PENNWALT CORPORATION (US) 1977-05-24 US disclosed
US-4009157-A POLYESTER FOAMING AGENTS, FREE RADICAL CATALYSTS PENNWALT CORPORATION (US) 1977-02-22 US disclosed
US-3993609-A ACID SENSITIVE AZO PROMOTERS PENNWALT CORPORATION (US) 1976-11-23 US disclosed