Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 7/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11151699 | 0.82 | MEN1 (0.32) | MEN1KMT2ACRHR1 | |
| SCHEMBL27843070 | 0.82 | CRHR1 (0.32) | MEN1KMT2ACRHR1 | |
| SCHEMBL11153799 | 0.82 | MEN1 (0.35) | MEN1KMT2ACRHR1 | |
| SCHEMBL11154313 | 0.82 | MEN1 (0.38) | MEN1KMT2ACRHR1 | |
| SCHEMBL2305613 | 0.78 | CYP1A2 (0.33) | — | |
| SCHEMBL28738889 | 0.78 | COMT (0.40) | CRHR1 | |
| SCHEMBL10822290 | 0.77 | CRHR1 (0.38) | MEN1KMT2ACRHR1 | |
| SCHEMBL11095259 | 0.77 | FBP1 (0.39) | MEN1KMT2ACRHR1 | |
| SCHEMBL11155424 | 0.77 | KDM4E (0.33) | MEN1KMT2ACRHR1 | |
| SCHEMBL11149480 | 0.77 | CRHR1 (0.32) | MEN1KMT2ACRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377693-A | 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners | MONSANTO COMPANY (US) | 1983-03-22 | — | — | US | disclosed |
| US-4377054-A | Seed coated with 2-chloro-4,5-disubstituted-thiazole derivatives which are herbicidal safeners | MONSANTO COMPANY (US) | 1983-03-22 | — | — | US | disclosed |
| EP-0027019-B1 | 2-CHLORO-4,5-DISUBSTITUTED-THIAZOLES, PROCESS FOR THEIR PREPARATION, USE AS ANTIDOTES AGAINST DAMAGE CAUSED BY HERBICIDES AND MIXTURES CONTAINING THEM | MONSANTO COMPANY (US) | 1983-02-16 | — | — | EP | disclosed |
| US-4371389-A | ACETANILIDE HERBICIDES, SORGHUM | MONSANTO COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
| US-4284426-A | 2-Chloro-4,5-disubstituted-thiazoles useful as herbicidal safeners | MONSANTO COMPANY (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0027019-A1 | 2-Chloro-4,5-disubstituted-thiazoles, process for their preparation, use as antidotes against damage caused by herbicides and mixtures containing them | MONSANTO COMPANY (US) | 1981-04-15 | — | — | EP | disclosed |