Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11159937 | 0.98 | EPHX2 (0.51) | EPHX2EPHX1P2RX7NPC1RAB9A | |
| SCHEMBL1075086 | 0.83 | EPHX2 (0.55) | EPHX2EPHX1P2RX7NPC1RAB9A | |
| SCHEMBL3362927 | 0.77 | EPHX2 (0.63) | EPHX2EPHX1P2RX7NPC1RAB9A | |
| Amantadine SCHEMBL8154960 | 0.72 | LMNA (0.61) | EPHX2EPHX1P2RX7NPC1RAB9A | |
| SCHEMBL1779571 | 0.72 | EPHX1 (0.58) | EPHX2EPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1074947 | 0.72 | TRPV6 (0.61) | EPHX2EPHX1P2RX7NPC1RAB9A | |
| SCHEMBL11149799 | 0.71 | EPHX2 (0.60) | EPHX2P2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10395199 | 0.71 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11159933 | 0.70 | EPHX2 (0.58) | EPHX2P2RX7SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL1937671 | 0.70 | NPC1 (0.84) | EPHX2EPHX1NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002066-B1 | 2-ADAMANTYL HYDRAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Teva Pharmaceutical Industries Limited (IL) | 1983-05-25 | — | — | EP | claimed |
| EP-0002066-A1 | 2-Adamantyl hydrazines and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | claimed |
| EP-0002066-B1 | 2-ADAMANTYL HYDRAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Teva Pharmaceutical Industries Limited (IL) | 1983-05-25 | — | — | EP | disclosed |
| US-4254128-A | 2-Adamantyl hydrazines and biocidal compositions thereof | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1981-03-03 | — | — | US | disclosed |