Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415350 | 0.87 | HTT (0.75) | TDP1HTTALDH1A1KMT2AMEN1 | |
| Salicylic Acid SCHEMBL6547019 | 0.86 | TDP1 (0.70) | TDP1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL9574717 | 0.85 | HTT (0.73) | TDP1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL3807238 | 0.84 | TSHR (0.56) | HTTALDH1A1KMT2AMEN1POLB | |
| Benzyl Salicylate SCHEMBL29411199 | 0.83 | TDP1 (0.75) | TDP1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL30710169 | 0.83 | TDP1 (0.52) | TDP1HTTALDH1A1KMT2AGAA | |
| SCHEMBL29687865 | 0.82 | ALDH1A1 (0.65) | TDP1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL38459 | 0.82 | ALDH1A1 (0.69) | TDP1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL27344933 | 0.81 | ALDH1A1 (0.68) | TDP1HTTALDH1A1KMT2AMEN1 | |
| SCHEMBL27320205 | 0.81 | ALDH1A1 (0.68) | TDP1HTTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080271-A1 | Indomethacin phenyl ester derivatives, their use, and compositions containing them | TEIKOKU KAGAKU SANGYO K.K. (JP) | 1983-06-01 | — | — | EP | disclosed |