Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.33 |
| ▸ | ADH1A | P07327 | 2/20 | 0.33 |
| ▸ | ADH7 | P40394 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566376 | 0.97 | EPHX1 (0.40) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL177856 | 0.95 | TSHR (0.46) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL1793351 | 0.92 | EPHX1 (0.46) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL1792344 | 0.92 | EPHX1 (0.46) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL1793038 | 0.92 | EPHX1 (0.46) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL1797346 | 0.92 | GRIN2D (0.41) | TSHRALDH1A1EPHX1GRIN2DGRIN3B | |
| SCHEMBL10939367 | 0.86 | — | — | |
| SCHEMBL7282001 | 0.84 | EPHX1 (0.62) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL2377046 | 0.83 | ALDH1A1 (0.43) | TSHRALDH1A1EPHX1NAAAMEN1 | |
| SCHEMBL10879464 | 0.83 | SMN1; SMN2 (0.42) | TSHRALDH1A1EPHX1NAAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4369181-A | Process for treating proliferative skin diseases using certain 6,8-substituted ribofuranosylpurine-3',5'-cyclic phosphates | SRI INTERNATIONAL (US) | 1983-01-18 | — | — | US | claimed |