Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11151714 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2EPHX2EPHX1LMNAHTT | |
| SCHEMBL839161 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2EPHX2EPHX1LMNAHTT | |
| SCHEMBL839162 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2EPHX2EPHX1LMNAHTT | |
| SCHEMBL8812116 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2EPHX2EPHX1LMNAHTT | |
| Hydrochloric Acid SCHEMBL5988469 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2EPHX2EPHX1LMNAHTT | |
| Hydrochloric Acid SCHEMBL5988473 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2EPHX2EPHX1LMNAHTT | |
| SCHEMBL11152670 | 0.78 | ALDH1A1 (0.44) | SMN1; SMN2EPHX2LMNAHTTKMT2A | |
| SCHEMBL11153662 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2EPHX2EPHX1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL11152864 | 0.77 | ALDH1A1 (0.43) | SMN1; SMN2EPHX2LMNAHTTKMT2A | |
| Hydrochloric Acid SCHEMBL11155254 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2EPHX2EPHX1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002066-B1 | 2-ADAMANTYL HYDRAZINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Teva Pharmaceutical Industries Limited (IL) | 1983-05-25 | — | — | EP | claimed |