SCHEMBL839161

SCHEMBL839161

CC(NC12CC3CC(CC(C3)C1)C2)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.53
EPHX2 P34913 7/20 0.47
EPHX1 P07099 2/20 0.47
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL839162 1.00 SMN1; SMN2 (0.53) SMN1; SMN2EPHX2EPHX1LMNAHTT
SCHEMBL8812116 1.00 SMN1; SMN2 (0.53) SMN1; SMN2EPHX2EPHX1LMNAHTT
Hydrochloric Acid SCHEMBL5988473 0.98 SMN1; SMN2 (0.51) SMN1; SMN2EPHX2EPHX1LMNAHTT
Hydrochloric Acid SCHEMBL5988469 0.98 SMN1; SMN2 (0.51) SMN1; SMN2EPHX2EPHX1LMNAHTT
Valine SCHEMBL10724646 0.88 SLC7A5 (0.47) SMN1; SMN2EPHX2EPHX1LMNAHTT
SCHEMBL11154682 0.81 SMN1; SMN2 (0.50) SMN1; SMN2EPHX2EPHX1LMNAHTT
Hydrochloric Acid SCHEMBL11151714 0.79 SMN1; SMN2 (0.49) SMN1; SMN2EPHX2EPHX1LMNAHTT
SCHEMBL105165 0.73 GRIN2D (0.52) SMN1; SMN2EPHX2EPHX1LMNAHTT
SCHEMBL1758676 0.73 SMN1; SMN2 (0.58) SMN1; SMN2HTTALDH1A1
SCHEMBL5079704 0.69 GRIN2D (0.43) SMN1; SMN2EPHX2EPHX1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008077194-A1 RECEPTOR AGONISTS XENOME LTD (AU) 2008-07-03 WO claimed
US-6890902-B2 Cytotoxic modified lactoferrin peptides ALPHARMA AS (NO) 2005-05-10 US claimed
US-6586402-B1 LH-RH peptide analogues, their uses and pharmaceutical compositions containing them LABORATOIRE THERAMEX (MC) 2003-07-01 US claimed
US-20030022821-A1 Bioactive peptides ALPHARMA AS 2003-01-30 US claimed
EP-1109827-A2 BIOACTIVE PEPTIDES ALPHARMA AS (NO) 2001-06-27 EP claimed
WO-2000012542-A2 CYTOTOXIC LACTOFERRIN DERIVATIVES MODIFIED BY BULKY OR LIPOPHILIC MOIETIES ALPHARMA AS (NO) 2000-03-09 WO claimed
US-5679640-A BINDING TO MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) E.G. HLA-DR'S, TO INHIBIT HLA-DR RESTRICTED T CELL ACTIVATION; AUTOIMMUNE DISEASES; ANTIARTHRITIC AGENTS CYTEL CORPORATION (US) 1997-10-21 US claimed
EP-0652893-A1 KININOGENASE INHIBITORS SZELKE, Michael (GB) 1995-05-17 EP claimed
WO-1992004371-A1 KININOGENASE INHIBITORS FERRING PEPTIDE RESEARCH PARTNERSHIP KB (SE) 1992-03-19 WO claimed
WO-1992002543-A1 NOVEL IMMUNOSUPPRESSANT PEPTIDES CYTEL CORPORATION (US) 1992-02-20 WO claimed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2026-04-23 US disclosed
US-12569565-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2026-03-10 US disclosed
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS INC (US) 2026-01-01 US disclosed
US-20250325644-A1 ALK POLYPEPTIDES AND METHODS OF USE THEREOF ELICIO THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-0262318-A2 Renin-inhibiting amino acid derivatives MERCK PATENT GmbH (DE) 1988-04-06 EP disclosed
US-4721776-A Amino acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-26 US disclosed
EP-0222283-A2 Amino-acid derivatives MERCK PATENT GmbH (DE) 1987-05-20 EP disclosed
EP-0220665-A2 Peptides MERCK PATENT GmbH (DE) 1987-05-06 EP disclosed
EP-0118223-A1 Enzyme inhibitors Aktiebolaget Hässle (SE) 1984-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108618-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, FCGR1A, FCGR2A SMN1; SMN2 1799/4885EPHX2 4481/4885EPHX1 4621/4885
US-12569565-B2 Compositions and methods for the treatment of viral infections ALB, FCGR3B, FCGR1A SMN1; SMN2 2235/4885EPHX2 3020/4885EPHX1 2981/4885
US-20030022821-A1 Bioactive peptides VIP, LITAF, LNPEP SMN1; SMN2 3706/4885EPHX2 4683/4885EPHX1 4742/4885
US-20260000781-A1 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF FCGR2A, FCGR1A, FCGR3B SMN1; SMN2 2679/4885EPHX2 316/4885EPHX1 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.