Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10840340 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1CA2LMNASMN1; SMN2 | |
| SCHEMBL9306882 | 0.79 | ALDH1A1 (0.48) | KDM4EOPRK1GAAALDH1A1CA2 | |
| SCHEMBL11149909 | 0.76 | ALDH1A1 (0.67) | KDM4EGAAALDH1A1CA2CYP3A4 | |
| SCHEMBL10458612 | 0.76 | KDM4E (0.55) | KDM4EOPRK1GAAALDH1A1LMNA | |
| SCHEMBL8611143 | 0.76 | KDM4E (0.55) | KDM4EOPRK1GAAALDH1A1LMNA | |
| SCHEMBL10626033 | 0.76 | ALDH1A1 (0.51) | KDM4EGAAALDH1A1CA2CYP3A4 | |
| SCHEMBL29990459 | 0.76 | LMNA (0.60) | KDM4EALDH1A1CA2CYP3A4LMNA | |
| SCHEMBL5158739 | 0.75 | GSK3B (0.43) | KDM4EALDH1A1CA2CYP3A4LMNA | |
| SCHEMBL19404527 | 0.75 | TP53 (0.58) | KDM4EOPRK1GAAALDH1A1LMNA | |
| SCHEMBL5145421 | 0.75 | ALDH1A1 (0.48) | KDM4EALDH1A1CA2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382872-A | COBALT, COPPER, NICKEL | THE DOW CHEMICAL CO. (US) | 1983-05-10 | — | — | US | disclosed |
| US-4254087-A | Extraction of copper, nickel and cobalt using alkylaromatic sulfonic acids and chelating amines | THE DOW CHEMICAL COMPANY (US) | 1981-03-03 | — | — | US | disclosed |