SCHEMBL11155261

SCHEMBL11155261

CCOP(=O)(OC)N(CO)CO

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.40
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11154240 0.89 PPARD (0.44) PPARDTSHRTP53TDP1ACHE
SCHEMBL11153970 0.84
SCHEMBL11162327 0.83 MEN1 (0.32) MEN1KMT2A
SCHEMBL12410125 0.75 ACHE (0.45) PPARDTSHRTP53TDP1ACHE
SCHEMBL11155216 0.74 LPAR3 (0.52) TSHRMEN1KMT2A
SCHEMBL11159129 0.71 MEN1 (0.35) PPARDTSHRMEN1KMT2A
SCHEMBL6990161 0.71 PPARD (0.46) PPARDTSHRTP53TDP1ACHE
SCHEMBL11180948 0.69 TSHR (0.34) PPARDTSHRTP53TDP1CA12
SCHEMBL3289373 0.69 TSHR (0.48) PPARDTSHRTP53TDP1ACHE
SCHEMBL11150874 0.68 CYP3A4 (0.52) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0008939-B1 INTUMESCENT COMPOSITION GREAT LAKES CHEMICAL CORPORATION (US) 1983-02-16 EP disclosed
US-4345002-A CYCLIC NITROGEN COMPOUND, HYDROXY CONTAINING ORGANO-PHOSPHORUS COMPOUND, AND A PHOSPHORUS CONTAINING ACID GREAT LAKES CHEMICAL CORPORATION (US) 1982-08-17 US disclosed
US-4201677-A MELAMINE DERIVATIVE, HYDROXYAMINOMETHANE PHOSPHONATE OR PHOSPHORAMIDATE VELSICOL CHEMICAL CORPORATION (US) 1980-05-06 US disclosed
EP-0008938-A2 Intumescent composition GREAT LAKES CHEMICAL CORPORATION (US) 1980-03-19 EP disclosed
EP-0008939-A2 Intumescent composition GREAT LAKES CHEMICAL CORPORATION (US) 1980-03-19 EP disclosed