Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753200 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30423025 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8653076 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL617940 | 0.81 | GAA (0.70) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL25424041 | 0.79 | ATM (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL21882016 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL30626919 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL15688913 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL25424052 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL4384430 | 0.77 | SMN1; SMN2 (0.85) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088869-A | 3CL protease inhibitor and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| US-11518764-B2 | Substituted heteroaryls as inhibitors of the BCL6 BTB domain protein-protein interaction | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2022-12-06 | — | — | US | disclosed |
| US-20200331921-A1 | INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2020-10-22 | — | — | US | disclosed |
| WO-2019153080-A1 | INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-08-15 | — | — | WO | disclosed |
| US-8262949-B2 | Long wavelength shifted benzotriazole uv-absorbers and their use | BASF SE (DE) | 2012-09-11 | — | — | US | disclosed |
| US-8262949-B2 | Long wavelength shifted benzotriazole uv-absorbers and their use | BASF SE (DE) | 2012-09-11 | — | — | US | disclosed |
| US-8262949-B2 | Long wavelength shifted benzotriazole uv-absorbers and their use | BASF SE (DE) | 2012-09-11 | — | — | US | disclosed |
| EP-2032577-B1 | LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE | BASF SE (DE) | 2011-02-02 | — | — | EP | disclosed |
| EP-2032577-B1 | LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE | BASF SE (DE) | 2011-02-02 | — | — | EP | disclosed |
| US-20100163813-A1 | Long wavelength shifted benzotriazole uv-absorbers and their use | CIBA CORPORATION | 2010-07-01 | — | — | US | disclosed |
| US-20100163813-A1 | Long wavelength shifted benzotriazole uv-absorbers and their use | CIBA CORPORATION | 2010-07-01 | — | — | US | disclosed |
| US-20100163813-A1 | Long wavelength shifted benzotriazole uv-absorbers and their use | CIBA CORPORATION | 2010-07-01 | — | — | US | disclosed |
| EP-2032577-A1 | LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE | Ciba Holding Inc. (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008000646-A1 | LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE | CIBA HOLDING INC. (CH) | 2008-01-03 | — | — | WO | disclosed |
| WO-2008000646-A1 | LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE | CIBA HOLDING INC. (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518764-B2 | Substituted heteroaryls as inhibitors of the BCL6 BTB domain protein-protein interaction | BCL6, BCL6B, BCL3 | SMN1; SMN2 3475/4885NPC1 406/4885RAB9A 2968/4885 |
| US-20200331921-A1 | INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | BCL6, BCL6B, BCL3 | SMN1; SMN2 3429/4885NPC1 401/4885RAB9A 3117/4885 |
| US-20100163813-A1 | Long wavelength shifted benzotriazole uv-absorbers and their use | SULT1A1, GABBR1, TPMT | SMN1; SMN2 3455/4885NPC1 2678/4885RAB9A 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.