Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143527 | 0.86 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11148070 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11150635 | 0.85 | ALDH1A1 (0.66) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11149177 | 0.83 | ALDH1A1 (0.75) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11144952 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11144945 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11143761 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11146999 | 0.77 | L3MBTL1 (0.46) | ALDH1A1LMNACYP1A2KMT2AMEN1 | |
| SCHEMBL11148775 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11148886 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | claimed |
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |