Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718553 | 0.87 | MAOA (0.53) | ARMAOAMAOBKMT2AXDH | |
| SCHEMBL21876221 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ARHTR2A | |
| SCHEMBL21876219 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ARHTR2A | |
| SCHEMBL29372177 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EUSP2ARHTR2A | |
| SCHEMBL18722119 | 0.80 | USP30 (0.47) | ARMAOAMAOB | |
| SCHEMBL9325871 | 0.80 | PDE4A (0.59) | ALDH1A1KDM4EPDE4BPDE4APDE4C | |
| SCHEMBL29038963 | 0.78 | MAOA (0.44) | ARHTR2AMAOAMAOBKMT2A | |
| SCHEMBL7723660 | 0.77 | PDE4B (0.49) | ALDH1A1KDM4EHTR2APDE4BPDE4A | |
| SCHEMBL4175149 | 0.76 | CHEK1 (0.53) | ARHTR2APDE4BQDPR | |
| SCHEMBL9291610 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2ARHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1983000333-A1 | ANTI-HYPERTENSOR, HETEROCYCLICALLY DI-ORTHOSUBSTITUTED PHENOLS | TEULON, JEAN-MARIE | 1983-02-03 | — | — | WO | disclosed |
| EP-0070779-A2 | Di-ortho-substituted phenols of which one of the substitutions is a heterocycle, process for their preparation, anti-hypertensive medicines containing them and synthesis intermediates | CARPIBEM (CENTRE D'ACTIVITE ET DE RECHERCHE PHARMACEUTIQUE INDUSTRIELLE BIOLOGIQUE ET MEDICALE) Société Anonyme dite: (FR) | 1983-01-26 | — | — | EP | disclosed |