SCHEMBL1115741

SCHEMBL1115741

CC(C)(C)CC(C)(C)c1ccc(O)c(C(C)(C)c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
CYP2D6 P10635 3/20 0.48
HIF1A Q16665 1/20 0.48
SHBG P04278 1/20 0.47
ESR1 P03372 6/20 0.44
ESR2 Q92731 4/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
PGR P06401 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
MAPT P10636 1/20 0.44
DRD1 P21728 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
PDE4A P27815 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29499209 1.00 CYP3A4 (0.48) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL7785231 0.88 SHBG (0.47) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL7522926 0.88 ESR1 (0.50) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL11208832 0.88 ESR1 (0.49) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL6862843 0.86 CYP3A4 (0.47) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL11153766 0.84 ESR1 (0.43) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL28041166 0.84 SHBG (0.46) CYP3A4CYP2D6HIF1ASHBGESR1
SCHEMBL745012 0.83 ESR1 (0.59) CYP3A4CYP2D6ESR1ESR2ALDH1A1
SCHEMBL29547368 0.83 ESR1 (0.59) CYP3A4CYP2D6ESR1ESR2ALDH1A1
SCHEMBL768277 0.83 SHBG (0.57) CYP3A4CYP2D6HIF1ASHBGESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084626-A Synthesis method of o-cumyl-p-tert-octylphenol 江苏极易新材料有限公司 2024-05-28 CN claimed
US-20190025465-A1 FUNCTIONAL EYEGLASS LENS FOR BLOCKING ULTRAVIOLET AND BLUE LIGHT Chemiglass Corporation (KR) 2019-01-24 US claimed
EP-3364236-A1 FUNCTIONAL EYEGLASS LENS FOR BLOCKING ULTRAVIOLET AND BLUE LIGHT Chemiglas Corporation (KR) 2018-08-22 EP claimed
CN-105503534-A Preparation method of 2-cumyl-4-tert-octylphenol RIANLON CORP 2016-04-20 CN claimed
US-20250101178-A1 HIGH MOLECULAR WEIGHT POLYESTERAMIDES SOLUTIA INC. (US) 2025-03-27 US disclosed
CN-118598909-B Preparation and application of OP bidentate fifth subgroup pentavalent metal complex 天津大学 2025-01-24 CN disclosed
CN-118598909-A Preparation and application of OP bidentate fifth subgroup pentavalent metal complex 天津大学 2024-09-06 CN disclosed
US-20240174857-A1 POLYESTERAMIDES, PROCESSES FOR THE PREPARATION THEREOF, AND POLYESTERAMIDE COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2024-05-30 US disclosed
CN-118084626-A Synthesis method of o-cumyl-p-tert-octylphenol 江苏极易新材料有限公司 2024-05-28 CN disclosed
CN-118084626-A Synthesis method of o-cumyl-p-tert-octylphenol 江苏极易新材料有限公司 2024-05-28 CN disclosed
US-11926740-B2 Resin composition, film, optical filter, image display device, solid-state imaging element, and compound FUJIFILM CORPORATION (JP) 2024-03-12 US disclosed
US-11845864-B2 Interlayers comprising polyesteramide compositions SOLUTIA INC. (US) 2023-12-19 US disclosed
US-20010007886-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2001-07-12 US disclosed
US-6166218-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 US disclosed
US-5977219-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-02 US disclosed
CN-1183442-A Benzotriazole UV absorbers having enhanced durability CIBA SC HOLDING AG (CH) 1998-06-03 CN disclosed
EP-0034836-B1 PROCESS FOR PREPARING NITROAZO BENZENES CIBA-GEIGY AG (CH) 1983-07-13 EP disclosed
US-4347180-A High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes CIBA-GEIGY CORPORATION (US) 1982-08-31 US disclosed
US-4275004-A High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes CIBA-GEIGY CORPORATION (US) 1981-06-23 US disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed