Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 6/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115741 | 0.88 | CYP3A4 (0.48) | SHBGCYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL29499209 | 0.88 | CYP3A4 (0.48) | SHBGCYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL11153766 | 0.84 | ESR1 (0.43) | SHBGCYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL4629051 | 0.83 | SHBG (0.57) | SHBGCYP3A4ESR1ALDH1A1HIF1A | |
| SCHEMBL647966 | 0.83 | ESR1 (0.59) | CYP3A4ESR1ESR2ALDH1A1CNR1 | |
| SCHEMBL28041166 | 0.81 | SHBG (0.46) | SHBGCYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL11208832 | 0.78 | ESR1 (0.49) | SHBGCYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL7522926 | 0.78 | ESR1 (0.50) | SHBGCYP3A4ESR1ESR2ALDH1A1 | |
| SCHEMBL1925358 | 0.76 | ESR1 (0.59) | CYP3A4ESR1ESR2ALDH1A1CNR1 | |
| SCHEMBL68434 | 0.76 | SHBG (0.61) | SHBGCYP3A4ESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007886-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2001-07-12 | — | — | US | disclosed |