Acetophenone

Acetophenone

SCHEMBL11157653

CC(=O)c1ccccc1.CCCOC(C)(C)C(C)(C)OCCC

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 4/20 0.45
MAOB P27338 2/20 0.44
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
HTR1A P08908 1/20 0.42
CYP2D6 P10635 1/20 0.42
SCN1A P35498 1/20 0.42
SLC6A3 Q01959 1/20 0.42
SCN5A Q14524 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetophenone SCHEMBL27691350 0.83 LMNA (0.58) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
Acetophenone SCHEMBL11157652 0.83 LMNA (0.50) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
Acetophenone SCHEMBL460178 0.80 SMN1; SMN2 (0.60) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
Acetophenone SCHEMBL28521014 0.80 LMNA (0.65) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
Acetophenone SCHEMBL7182516 0.77 SMN1; SMN2 (0.52) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
Propiophenone SCHEMBL11148945 0.77 SMN1; SMN2 (0.50) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
Acetophenone SCHEMBL28186100 0.77 CES2 (0.60) LMNAALDH1A1SMN1; SMN2MAPTHPGD
Acetophenone SCHEMBL10610347 0.77 SMN1; SMN2 (0.56) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT
SCHEMBL14514224 0.76 LMNA (0.55) LMNAALDH1A1KMT2ATDP1HTR1A
Acetophenone SCHEMBL10397586 0.76 SMN1; SMN2 (0.60) LMNAALDH1A1SMN1; SMN2L3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026248-B Thermosetting epoxy resin compositions for making outdoor articles and articles obtained therefrom 亨斯迈先进材料许可(瑞士)有限公司 2021-12-10 CN disclosed
EP-3430629-B1 ELECTRICAL INSULATION SYSTEM BASED ON EPOXY RESINS FOR GENERATORS AND MOTORS HUNTSMAN ADV MAT LICENSING SWITZERLAND GMBH (CH) 2020-03-18 EP disclosed
US-20190080818-A1 Electrical Insulation System Based on Epoxy Resins for Generators and Motors HUNSTMAN ADVANCED MATERIALS LICENSING (SWITZERLAND) GMBH (CH) 2019-03-14 US disclosed
EP-3430629-A1 ELECTRICAL INSULATION SYSTEM BASED ON EPOXY RESINS FOR GENERATORS AND MOTORS Huntsman Advanced Materials Licensing (Switzerland) GmbH (CH) 2019-01-23 EP disclosed
US-20180371153-A1 A Thermosetting Epoxy Resin Composition for the Preparation of Outdoor Articles, and the Articles Obtained Therefrom HUNTSMAN INTERNATIONAL LLC 2018-12-27 US disclosed
EP-3317318-A1 A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF OUTDOOR ARTICLES, AND THE ARTICLES OBTAINED THEREFROM Huntsman Advanced Materials Licensing (Switzerland) GmbH (CH) 2018-05-09 EP disclosed
WO-2017001182-A1 A THERMOSETTING EPOXY RESIN COMPOSITION FOR THE PREPARATION OF OUTDOOR ARTICLES, AND THE ARTICLES OBTAINED THEREFROM HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2017-01-05 WO disclosed
US-4393185-A EPOXIDES CIBA-GEIGY CORPORATION (US) 1983-07-12 US disclosed
US-4336366-A Thermally polymerizable mixtures and processes for the thermally-initiated polymerization of cationically polymerizable compounds CIBA-GEIGY CORPORATION (US) 1982-06-22 US disclosed