SCHEMBL1115801

SCHEMBL1115801

CCC(N)(O)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.43
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
THRB P10828 1/20 0.30
KMT2A Q03164 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27775120 1.00 DGAT1 (0.43) DGAT1CA12CA1CA7CA14
SCHEMBL27795979 1.00 DGAT1 (0.43) DGAT1CA12CA1CA7CA14
SCHEMBL25388987 0.84 DGAT1 (0.41) DGAT1CA1TDP1
SCHEMBL30690429 0.82 DGAT1 (0.40) DGAT1
SCHEMBL6535584 0.81 FDPS (0.38) DGAT1CA12CA1CA7CA14
SCHEMBL14485423 0.81 DGAT1 (0.48) DGAT1CA12CA1CA7CA14
SCHEMBL1433036 0.81 DGAT1 (0.43) DGAT1CA12CA1CA7CA14
SCHEMBL14485421 0.81 DGAT1 (0.48) DGAT1CA12CA1CA7CA14
SCHEMBL12860069 0.81 DGAT1 (0.48) DGAT1CA12CA1CA7CA14
SCHEMBL8489844 0.81 DGAT1 (0.43) DGAT1CA12CA1CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449065-B NAC modified blood purification membrane and preparation method thereof 中南大学湘雅医院 2023-09-22 CN claimed
CN-115449065-A NAC (N-acetyl-D) -modified blood purification membrane and preparation method thereof 中南大学湘雅医院 2022-12-09 CN claimed
CN-105542154-A Polylactic acid preparation method SHAANXI YUHANG ELECTRONICS CO LTD 2016-05-04 CN claimed
EP-1511471-B9 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR DELIVERING ACTIVE PRINCIPLES AND METHOD FOR PREPARING SAME FLAMEL TECH SA (FR) 2011-04-20 EP claimed
EP-1511471-B1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR DELIVERING ACTIVE PRINCIPLES AND METHOD FOR PREPARING SAME FLAMEL TECH SA (FR) 2011-02-02 EP claimed
JP-2005529888-A 2005-10-06 JP claimed
EP-1511471-A1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR DELIVERING ACTIVE PRINCIPLES AND METHOD FOR PREPARING SAME Flamel Technologies (FR) 2005-03-09 EP claimed
WO-2003090727-A1 COLLOIDAL SUSPENSION OF SUBMICRONIC PARTICLES FOR DELIVERING ACTIVE PRINCIPLES AND METHOD FOR PREPARING SAME FLAMEL TECHNOLOGIES (FR) 2003-11-06 WO claimed
CN-115449065-B NAC modified blood purification membrane and preparation method thereof 中南大学湘雅医院 2023-09-22 CN disclosed
CN-115449065-A NAC (N-acetyl-D) -modified blood purification membrane and preparation method thereof 中南大学湘雅医院 2022-12-09 CN disclosed
EP-3366680-B1 DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES PARION SCIENCES INC (US) 2020-05-13 EP disclosed
EP-2497785-B1 Hyaluronic acid derivative and drug containing the same SEIKAGAKU KOGYO CO LTD (JP) 2018-09-12 EP disclosed
EP-3366680-A1 DENDRIMER LIKE AMINO AMIDES POSSESSING SODIUM CHANNEL BLOCKER ACTIVITY FOR THE TREATMENT OF DRY EYE AND OTHER MUCOSAL DISEASES Parion Sciences, Inc. (US) 2018-08-29 EP disclosed
EP-3363463-A2 HYALURONIC ACID DERIVATIVE AND DRUG CONTAINING THE SAME Seikagaku Corporation (JP) 2018-08-22 EP disclosed
EP-0999220-A2 Low molecular weight peptidomimetic growth hormone secretagogues Genentech, Inc. (US) 2000-05-10 EP disclosed
WO-2000012509-A2 COLLECTIONS OF COMPOUNDS SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed
WO-2000012508-A2 PYRROLBENZODIAZEPINES SPIROGEN LIMITED (GB) 2000-03-09 WO disclosed
US-6034216-A Low molecular weight peptidomimetic growth hormone secretagogues GENENTECH INC. (US) 2000-03-07 US disclosed
US-5798337-A USED TO PROMOTE GROWTH IN MAMMALS EITHER ALONE OR IN COMBINATION WITH OTHER GROWTH PROMOTING COMPOUNDS GENENTECH, INC. (US) 1998-08-25 US disclosed
WO-1997021666-A1 ARYLETHANOLAMINE DERIVATIVES AND THEIR USE AS AGONISTS OF ATYPICAL BETA-ADRENOCEPTORS GLAXO GROUP LIMITED (GB) 1997-06-19 WO disclosed