Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHKA | P35790 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453194 | 0.82 | FSCN1 (0.46) | FSCN1TSHRCHKAKMT2AGAA | |
| SCHEMBL11156542 | 0.79 | MAPT (0.45) | FSCN1CHKAKMT2AMAPTHPGD | |
| SCHEMBL28984819 | 0.79 | HSD17B10 (0.39) | FSCN1PTGS2TSHRHSD17B10KMT2A | |
| SCHEMBL11160853 | 0.78 | PTGS2 (0.54) | PTGS2HSD17B10CHKAPOLBALDH1A1 | |
| SCHEMBL28984816 | 0.76 | PTGS2 (0.40) | FSCN1PTGS2TSHRCHKAKMT2A | |
| SCHEMBL11153653 | 0.73 | TSHR (0.47) | FSCN1TSHRGAACYP3A4ALDH1A1 | |
| SCHEMBL2616324 | 0.72 | GAA (0.59) | FSCN1PTGS2TSHRHSD17B10KMT2A | |
| SCHEMBL11435307 | 0.71 | MAPK1 (0.46) | PTGS2TSHRKMT2AGAAPOLB | |
| SCHEMBL926427 | 0.71 | APP (0.52) | PTGS2TSHRHSD17B10KMT2ACYP3A4 | |
| SCHEMBL10913732 | 0.69 | PTGS2 (0.44) | PTGS2CHKAKMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013144-B1 | SUBSTITUTED DIPHENYLAMINE DERIVATIVES, COMPOSITIONS AND HERBICIDAL USES THEREOF, AND PROCESSES FOR THEIR PREPARATION | ICI AUSTRALIA LIMITED (AU) | 1983-02-23 | — | — | EP | disclosed |
| EP-0013144-A1 | Substituted diphenylamine derivatives, compositions and herbicidal uses thereof, and processes for their preparation | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |