Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432404 | 0.81 | TUBB4A (0.48) | MAPK1CSF1REGFRSMN1; SMN2LMNA | |
| SCHEMBL11440205 | 0.79 | MAPT (0.38) | MAPK1PTGS2MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL11453631 | 0.76 | PTGS2 (0.43) | MAPK1GAAPTGS2MAPTKDM4E | |
| SCHEMBL11497819 | 0.75 | MAP4K4 (0.47) | GAAL3MBTL1LIPECYP2C9TSHR | |
| SCHEMBL11440171 | 0.73 | L3MBTL1 (0.47) | MAPTKDM4EL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL9682919 | 0.72 | EGFR (0.43) | GAACSF1REGFRL3MBTL1ALDH1A1 | |
| SCHEMBL11158404 | 0.71 | FSCN1 (0.50) | GAAPTGS2MAPTKDM4EALDH1A1 | |
| SCHEMBL11160853 | 0.70 | PTGS2 (0.54) | MAPK1PTGS2KDM4EALDH1A1POLB | |
| SCHEMBL11270290 | 0.70 | PTGS2 (0.39) | MAPK1PTGS2MAPTEGFRSMN1; SMN2 | |
| SCHEMBL10730866 | 0.69 | CSF1R (0.59) | GAAMAPTCSF1REGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013145-A2 | Substituted anilinopyridines, processes for their preparation and intermediates for use therein, compositions and herbicidal use thereof | ICI AUSTRALIA LIMITED (AU) | 1980-07-09 | — | — | EP | disclosed |