Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11166965 | 0.93 | DPP4 (0.47) | ACEACE2 | |
| SCHEMBL11156627 | 0.90 | ALDH1A1 (0.44) | — | |
| SCHEMBL11471699 | 0.89 | — | — | |
| SCHEMBL11159990 | 0.89 | THRB (0.51) | — | |
| SCHEMBL11157569 | 0.88 | ACE (0.56) | ACEACE2 | |
| SCHEMBL11168257 | 0.87 | ACE (0.44) | ACE | |
| SCHEMBL11175895 | 0.87 | ACE (0.44) | ACE | |
| SCHEMBL11466706 | 0.87 | F2 (0.45) | ACE | |
| SCHEMBL11156600 | 0.86 | ACE (0.45) | ACE | |
| SCHEMBL11162523 | 0.85 | KMT2A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010347-B1 | NOVEL SUBSTITUTED OMEGA-AROYL(PROPIONYL OR BUTYRYL)-L-PROLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |
| US-4226775-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0010347-A1 | Novel substituted omega-aroyl(propionyl or butyryl)-L-prolines, pharmaceutical compositions containing them and processes for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |