Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | CDK9 | P50750 | 2/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115898 | 0.92 | MAPT (0.44) | FABP3FABP4MAPTDYRK1ACDK9 | |
| SCHEMBL1116255 | 0.86 | MAPT (0.46) | FABP3FABP4MAPTDYRK1AMEN1 | |
| SCHEMBL2926922 | 0.84 | MAPT (0.44) | FABP3FABP4MAPTCSF1RMEN1 | |
| SCHEMBL12856631 | 0.84 | MAPT (0.44) | FABP3FABP4MAPTCSF1RMEN1 | |
| SCHEMBL12856619 | 0.84 | MAPT (0.44) | FABP3FABP4MAPTCSF1RMEN1 | |
| SCHEMBL1116024 | 0.84 | MAPT (0.44) | FABP3FABP4MAPTCSF1RMEN1 | |
| SCHEMBL12856603 | 0.82 | MAPT (0.46) | FABP3FABP4MAPTDYRK1ACDK9 | |
| SCHEMBL1116205 | 0.81 | MAPT (0.42) | FABP3FABP4MAPTMEN1KMT2A | |
| SCHEMBL1116014 | 0.81 | MAPT (0.46) | MAPTCSF1RMEN1KMT2A | |
| SCHEMBL1115894 | 0.79 | MAPT (0.44) | MAPTCSF1RMEN1KMT2AHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281819-A1 | Benzimidazolyl or benzoxazolyl derivatives | Novartis AG (CH) | 2011-02-09 | — | — | EP | disclosed |
| EP-2281819-A1 | Benzimidazolyl or benzoxazolyl derivatives | Novartis AG (CH) | 2011-02-09 | — | — | EP | disclosed |
| US-20090298824-A1 | Organic compounds | PRESS NEIL J | 2009-12-03 | — | — | US | disclosed |
| US-20090298824-A1 | Organic compounds | PRESS NEIL J | 2009-12-03 | — | — | US | disclosed |
| US-20090298824-A1 | Organic compounds | PRESS NEIL J | 2009-12-03 | — | — | US | disclosed |
| EP-1709015-A1 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005070906-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298824-A1 | Organic compounds | CXCR2, CXCR3, CXCR1 | FABP3 1991/4885FABP4 1356/4885MAPT 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.