SCHEMBL1115967

SCHEMBL1115967

Cc1ccc(CC2=CC=CC2)cc1.[V]

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.37
DAO P14920 1/20 0.36
HTR6 P50406 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2A6 P11509 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
SRD5A2 P31213 1/20 0.34
KMT2A Q03164 2/20 0.33
AGXT P21549 2/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
ACHE P22303 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12815569 0.98 IDO1 (0.38) IDO1DAOHTR6CYP1A2CYP2A6
SCHEMBL11554501 0.89 ALDH1A1 (0.32) KMT2AALDH1A1TDP1
SCHEMBL21494670 0.81 IDO1 (0.34) IDO1DAOHTR6CYP1A2CYP2A6
SCHEMBL7933390 0.80 TAAR1 (0.39) IDO1DAOHTR6TAAR1AGXT
SCHEMBL2836936 0.79 CALM1 (0.46) CYP1A2TAAR1ALDH1A1LMNA
SCHEMBL12815819 0.78 IDH1 (0.34)
SCHEMBL9143779 0.78 CALM1 (0.44) CYP1A2TAAR1LMNA
SCHEMBL9144956 0.78 CALM1 (0.44) CYP1A2TAAR1LMNA
SCHEMBL12814980 0.77 ESR1 (0.38) ALDH1A1HTTLMNA
SCHEMBL12814968 0.77 MGAM (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2028196-B1 METHOD FOR PRODUCING POLYBUTADIENE UBE INDUSTRIES (JP) 2011-02-02 EP disclosed
EP-1249457-B1 Method of producing a polymer UBE INDUSTRIES (JP) 2005-07-20 EP disclosed
US-6521726-B1 Method of producing a polymer UBE INDUSTRIES, LTD. (JP) 2003-02-18 US disclosed
EP-1249457-A2 Method of producing a polymer Ube Industries, Ltd. (JP) 2002-10-16 EP disclosed