Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ametryne SCHEMBL65196 | 1.00 | POLB (0.54) | POLBGAAALDH1A1HTTCYP1A2 | |
| Prometryn SCHEMBL7945620 | 1.00 | POLB (0.54) | POLBGAAALDH1A1HTTCYP1A2 | |
| Ametryne SCHEMBL29368218 | 1.00 | POLB (0.54) | POLBGAAALDH1A1HTTCYP1A2 | |
| Ametryne SCHEMBL8541067 | 1.00 | POLB (0.54) | POLBGAAALDH1A1HTTCYP1A2 | |
| Ametryne SCHEMBL11801379 | 0.94 | POLB (0.49) | POLBGAAALDH1A1HTTCYP1A2 | |
| Ametryne SCHEMBL31093673 | 0.92 | GAA (0.58) | POLBGAAALDH1A1HTTCYP1A2 | |
| Prometryn SCHEMBL29456674 | 0.92 | GAA (0.58) | POLBGAAALDH1A1HTTCYP1A2 | |
| Ametryne SCHEMBL8812043 | 0.92 | GAA (0.58) | POLBGAAALDH1A1HTTCYP1A2 | |
| Prometryn SCHEMBL10969844 | 0.92 | GAA (0.58) | POLBGAAALDH1A1HTTCYP1A2 | |
| Dimethametryne SCHEMBL6364817 | 0.92 | HTT (0.49) | POLBGAAALDH1A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032242-B1 | 4H-3,1-BENZOXAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN INHIBITING THE GROWTH OF UNWANTED PLANTS | BASF Aktiengesellschaft (DE) | 1983-12-14 | — | — | EP | disclosed |